Description

Edited by Aria Fallah; Edited by George M. Ibrahim; Edited by Alexander G. Weil

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Pediatric Epilepsy Surgery Techniques: Controversies and Evidence offers clinicians a roadmap for navigating the complex decision-making process involved in selecting surgical interventions for children with drug-resistant epilepsy. Over the last decade, the landscape of pediatric epilepsy surgery has undergone substantial transformation, marked by the introduction of several emerging technologies that are now supported by an expanding body of evidence, yet leading to a wide range of treatment practices. This book addresses several decision-making dichotomies in pediatric epilepsy surgery, both in terms of established and novel surgical modalities and techniques. The book explores long-standing debated topics, such as the relative benefits of disconnective compared to resective strategies, the utility of surgical adjuncts like intra-operative electrocorticography, as well as rationales for different surgical approaches, namely selective amygdalo-hippocampectomy versus anteromesial temporal lobectomy. Further, it addresses dichotomies between traditional approaches and contemporary modalities, such as microsurgical resection versus laser interstitial thermal therapy. Chapters also offer comparisons of modern technologies, such as different neuromodulation strategies, including vagus nerve stimulation, deep brain stimulation, and responsive neurostimulation.This book provides readers with the relevant scientific literature and expert commentary to inform evidence-based approaches to surgical care in pediatric drug-resistant epilepsy.

Table of contents:
Part 1: Evidence in pediatric epilepsy surgery1. Evidence in pediatric epilepsy surgeryChurl-Su Kwon and Varun Ramanan Subramaniam2. Controversies in the timing of pediatric epilepsy surgery—is earlier better?Jarod L. RolandPart 2: Invasive investigation3. Electroencephalographic evaluation of epileptogenicity—traditional versus novel biomarkers to guide surgeryEroshini Swarnalingam and Julia Jacobs4. Invasive monitoring: stereoelectroencephalography (sEEG) versus subdural electrode (SDE) versus hybrid evaluationTaylor J. Abel, Luis Fernandez and Joseph GarciaPart 3: Resective or ablative surgery5. Intraoperative adjuncts to optimize the surgical treatment of drug-resistant epilepsy—do new tools improve outcome?Trang Tran, Frederic Leblond and Roy W.R. Dudley6. Medial temporal lobe epilepsy—selective amygdalohippocampectomy versus anterior temporal lobectomyChristian Dorfer7. Epilepsy in eloquent cortex: resection versus responsive neurostimulationSaadi Ghatan8. Lesional epilepsy: lesionectomy versus ECoG-guided resectionShimrit Sibony-Uliel and Jonathan Roth9. Insular/perisylvian epilepsy: Open resection versus stereotactic ablation (MR-guided laser ablation/radiofrequency thermocoagulation) versus responsive neurostimulationVincent Joris, Jessica Royer and Alexander G. WeilPart 4: Hypothalamic hamartoma10. Hypothalamic hamartoma—open surgery versus endoscopic surgery versus stereotactic radiosurgery versus stereotactic ablation (MR-guided laser ablation/Radiofrequency ablation) versus MRFUSSantiago Candela-Canto, Roberto Martınez Alvarez and Jose Hinojosa Mena-BernalPart 5: Tuberous sclerosis complex11. Resective surgery in tuberous sclerosis complex-related epilepsy: tuberectomy and tuberectomy plusShuli Liang, Zhirong Wei, Jiaqi Wang and Feng ZhaiPart 6: Disconnective procedures12. Functional hemispheric surgery—vertical versus lateral approachJia-Shu Chen, H. Westley Phillips and Aria Fallah13. Minimally invasive hemispherotomy—endoscopic, radiofrequency and robotic techniquesPoodipedi Sarat Chandra and Manjari Tripathi14. Lobar/multilobar epilepsy: resection versus disconnectionVejay N. Vakharia and Martin M. Tisdall15. Corpus callosotomy: anterior two-thirds (two-stage) versus complete (one-stage)Meena Vessell